Mortality and associated variables on the Cardiology floor during the first wave of the Covid-19 pandemic at the Edgardo Rebagliati Martins Hospital

Abstract

Objective: Evaluate mortality and associated variables in the population hospitalized on floor 11-Covid during the first wave of the Covid-19 pandemic through a multivariate model. Materials and methods: Retrospective cohort study carried out in 419 patients over 14 years of age, hospitalized on the 11-Covid floor, attended by cardiologists, enabled for the management of patients affected by Covid-19 at the Edgardo Rebagliati Martins Hospital during the first wave of the Covid-19 pandemic with confirmatory laboratory test. Results: overall mortality was 12.89%. The deceased population was older than its counterpart (64.85±14 years versus (vs) 56.66±14 years p=0.0001). Multivariate analysis showed that the variables significantly associated with mortality were: 1) PAFI (arterial oxygen pressure ratio/inspired oxygen fraction) <100, incidence rate ratio (IRR): 2.3, confidence interval (CI): 1.28-4.13 p=0.005, 2)
pulmonary involvement >75% IRR: 2.97 CI: 1.19-7.41 p=0.019 and 3) pulmonary involvement between 50-74.9% IRR 2.3 CI: 1.04-5.12 p=0.04, age >=60 years, IRR: 2.03 CI: 1.11-3.68 p=0.02, and clinical condition assessed at admission to the floor as “severe”: IRR: 2.87, CI: 1.55-5.3 p=0.001 a protective variable was the greatest number of days prior to hospitalization (prehospitalization) IRR: 0.9 CI: 0.84-0.97 p=0.003. Conclusion: Covid-19 mortality in our cohort was associated with the following conditions: age 60 years or older, percentage of lung involved greater than 50%, PAFI<100, and a protective factor was longer pre-hospitalization time.